ABSTRACT
Background: Malnutrition in under five children is prevalent widely. It affects growth as well as development; also causes higher morbidity and mortality among children significantly. This public health problem is multi-factorial. Aim and Objectives: This study was conducted to estimate the prevalence of under nutrition and its risk factors among children up to 2 years of age attending a tertiary health care institution of Kolkata. Material and methods: This cross-sectional study was conducted among children aged 0 � 23 months, attending the Immunization clinic of CMSDH, Kolkata, during December, 2019 朖anuary, 2020. Data were collected by interviewing the accompanying caregivers, anthropometric measurements of the study subjects and review of records. Results: Among 135 children studied, the prevalence of stunting was 14.1% (5.8% severely stunted), underweight was 9.7% (3.8% severely underweight), wasting was 18.5% (8.1% were SAM).Younger age group (0-6 months),boys and children having inappropriate feeding for age were at increased risk of under nutrition. Children having working mothers, birth spacing of <3 years, LBW and delayed initiation of breastfeeding (>1hour) were at higher risk of stunting and underweight. Incorrect age of introduction of complementary feeding had higher risk of wasting. Conclusion: Several risk factors for malnutrition were found which are amenable to prevention.
ABSTRACT
Background: Rubella infection in pregnant mothers is of great concern as it acts as a teratogen causing abortions, still births, intra-uterine foetal deaths and multiple birth defects. In India, rubella causes significant bad obstetric pregnancy outcome including congenital deformities due to lack of proper surveillance and immunization coverage with rubella vaccination. Aim: To determine Sero-prevalence of rubella IgM and IgG antibodies in Bad Obstetric History (BOH) pregnant women in Tertiary Rural Medical College in Eastern India. Materials and Methods: Cross sectional study was conducted from 1st January 2017 to 31st March 2017 on sera of 100 antenatal mothers with bad obstetric history aged between 20-40 years of age group with pregnancy of ≥18 wks. Rubella IgM and IgG antibodies were assessed by ELISA. Statistical Analysis: Percentage, proportions and ᵡ2 test were applied. Results: Eleven per cent (11%) sero-prevalence for IgM antibodies and 54% for IgG antibodies was observed with maximum sero-positivity among 20-25 years mothers. Repeated abortions were the commonest pregnancy outcome. Conclusion: All antenatal cases should be routinely screened for rubella, so that early diagnosis will help in proper management and foetal outcome and strong recommendation for universal coverage of MMR in early age group of children.
ABSTRACT
Background: Rubella infection in pregnant mothers is of great concern as it acts as a teratogen causing abortions, still births, intra-uterine foetal deaths and multiple birth defects. In India, rubella causes significant bad obstetric pregnancy outcome including congenital deformities due to lack of proper surveillance and immunization coverage with rubella vaccination. Aim: To determine Sero-prevalence of rubella IgM and IgG antibodies in Bad Obstetric History (BOH) pregnant women in Tertiary Rural Medical College in Eastern India. Materials and Methods: Cross sectional study was conducted from 1st January 2017 to 31st March 2017 on sera of 100 antenatal mothers with bad obstetric history aged between 20-40 years of age group with pregnancy of ≥18 wks. Rubella IgM and IgG antibodies were assessed by ELISA. Statistical Analysis: Percentage, proportions and ᵡ2 test were applied. Results: Eleven per cent (11%) sero-prevalence for IgM antibodies and 54% for IgG antibodies was observed with maximum sero-positivity among 20-25 years mothers. Repeated abortions were the commonest pregnancy outcome. Conclusion: All antenatal cases should be routinely screened for rubella, so that early diagnosis will help in proper management and foetal outcome and strong recommendation for universal coverage of MMR in early age group of children.
ABSTRACT
Though organ transplantation has evolved in many a ways over the years, it is not without the disadvantage of causing rejections. Cyclosporin, azathioprine and corticosteroids are time tested and efficacious; however each is accompanied with its own array of disadvantages. Sirolimus is a relatively new immunosuppressant isolated from a macrolide antibiotic. It may have a beneficial role in prophylaxis of rejection as well as treatment of refractory rejection. It also has antifungal, antitumor and anti-smooth muscle proliferative roles.